Likewise, there is a clear distinction between breeding and genetic engineering. Breeders manipulate indirectly the natural processes of gene selection and mutation that occur in nature. Breeders are unable, therefore, to turn genes on or off with precision or to create hybrids with genomic material so distinct as that of a dog and a jellyfish. In this sense, a distinctive trait of transgenic art is that the genetic material is manipulated directly: the foreign DNA is precisely integrated into the host genome. In addition to genetic transfer of existing genes from one species to another, we can also speak of "artist's genes," i.e., chimeric genes or new genetic information completely created by the artist through the complementary bases A (adenine) and T (thymine) or C (cytosine) and G (guanine). This means that artists now can not only combine genes from different species but easily write a DNA sequence on their word processors, email it to a commercial synthesis facility, and in less than a week receive a test tube with millions of molecules of DNA with the expected sequence.